Well, with changes like that i think a rework PvP zone debuff is in order, instead of flat skill, hp and gamma regen reduction (or in the case of extreme debuf complete disabling) it should be changed in such way that would merely balance the high level player stats to the low level ones. As in, giving players in level 15 PvP zone a fighting chance against lvl 55, while still enabling the high level player to use mutations and gear (not reducing all stats to 0).
That way people would not be forced into PvP zones they dont like (or ones that are flat out broken or bugged out *erhm*AlphaCoutry*erhm*) and they wouldn´t need to have alt-chars/ accounts for low(er) level zones.
Though I have no idea what kind of system could do this, while keeping everything balanced and without giving programmers a headache.