This problem has symptoms in-game that require logging out.
The worst symptom is that you can't get any new missions; when you click to accept the new mission it plays a sound like a very muted trumpet then nothing happens, the mission is not added to your list of missions regardless of whether you have an open tracking slot or not. the only fix for this has been re-logging, but you can't bring a toon back into play and when you try exit and restart there are no clones when the character selection screen loads.
These two events are always paired together as nearly as can tell...
good luck fixin' it!
hmm... to add to the previous post,..
was finally able to load a character and discovered the mission that would not add to our mission list was finally added in.
hope this info helps.
did not notice lag when this happened earlier.