I would very much like to get to the bottom of this problem too. I just reinstalled this game and tried to launch it again for the first time in a while, and I can't even get to the main menu before the game crashes to desktop with the same "Untrusted System File" error message in reference to EAC. I tried deleting the EAC subfolder in the APB installation directory, tried repairing the EAC installation, but none of that worked. Then I tried following arkup's advice and deleting the .dll file that was being specified in the error message, and that got rid of the "Untrusted System File" error, but the game still crashes at the same spot in the loading screen.
I don't think this problem has anything to do with AMD drivers, because I don't have an AMD card. The .dll files referenced in my error had to do with Microsoft C Redistributable. At this rate, it's not even clear that the problem is with EAC.